Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | IL2 | P60568 | 8/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256962 | 0.91 | POLB (0.41) | ALDH1A1LMNAPOLBUSP2KDM4E | |
| SCHEMBL8260160 | 0.88 | LMNA (0.38) | ALDH1A1LMNAPOLBIL2USP2 | |
| SCHEMBL8260246 | 0.87 | LMNA (0.39) | ALDH1A1LMNAPOLBIL2USP2 | |
| SCHEMBL8260033 | 0.83 | LMNA (0.36) | ALDH1A1LMNAPOLBIL2USP2 | |
| SCHEMBL8256827 | 0.82 | LMNA (0.38) | ALDH1A1LMNAPOLBIL2USP2 | |
| SCHEMBL8263037 | 0.82 | IL2 (0.46) | ALDH1A1LMNAPOLBIL2USP2 | |
| SCHEMBL8259732 | 0.82 | LMNA (0.37) | ALDH1A1LMNAPOLBIL2USP2 | |
| SCHEMBL8259823 | 0.80 | IL2 (0.46) | IL2 | |
| SCHEMBL8259763 | 0.79 | POLB (0.41) | ALDH1A1LMNAPOLBIL2USP2 | |
| SCHEMBL8256460 | 0.78 | IL2 (0.56) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081391-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-03 | — | — | WO | disclosed |