Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | IL2 | P60568 | 7/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256827 | 0.89 | LMNA (0.38) | LMNAPOLBIL2ADORA2AADORA1 | |
| SCHEMBL8260033 | 0.85 | LMNA (0.36) | LMNAPOLBIL2ALDH1A1USP2 | |
| SCHEMBL8260246 | 0.83 | LMNA (0.39) | LMNAPOLBIL2ALDH1A1USP2 | |
| SCHEMBL8261514 | 0.82 | IL2 (0.42) | LMNAPOLBIL2ADORA2AADORA1 | |
| SCHEMBL8260160 | 0.82 | LMNA (0.38) | LMNAPOLBIL2ALDH1A1USP2 | |
| SCHEMBL8252236 | 0.82 | ALDH1A1 (0.39) | LMNAPOLBIL2ALDH1A1USP2 | |
| SCHEMBL8260065 | 0.81 | IL2 (0.53) | IL2 | |
| SCHEMBL8260057 | 0.81 | IL2 (0.46) | IL2 | |
| SCHEMBL8257487 | 0.77 | POLB (0.40) | LMNAPOLBALDH1A1USP2KDM4E | |
| SCHEMBL15214064 | 0.74 | IL2 (0.43) | LMNAPOLBIL2USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081391-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-03 | — | — | WO | disclosed |