SCHEMBL825437

SCHEMBL825437

CC(C)(c1ccc(CN=C=O)o1)c1ccc(CN=C=O)o1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490975 0.80 LMNA (0.35)
SCHEMBL13884605 0.75 LMNA (0.32)
SCHEMBL845604 0.75 HTT (0.33)
SCHEMBL10993099 0.73 POLB (0.30)
SCHEMBL18864324 0.72 LMNA (0.31)
SCHEMBL30831884 0.70 LMNA (0.30)
SCHEMBL10983582 0.69 CYP2D6 (0.41)
SCHEMBL901068 0.69 ALDH1A1 (0.42)
SCHEMBL19681453 0.69
SCHEMBL28914402 0.68 CYP3A4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4496751-A Difunctional furan derivatives THE UNIVERSITY OF MANCHESTER INSTITUTE OF SCIENCE & TECHNOLOGY (GB) 1985-01-29 US claimed
EP-4340807-B1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MAT INC (US) 2026-01-28 EP disclosed
EP-4594382-A1 OPTIONALLY SILYLATED IONIC POLYURETHANE(S) Bostik SA (FR) 2025-08-06 EP disclosed
EP-3233981-B1 PROCESS FOR MAKING A WATERBORNE DISPERSION COMPRISING A CATIONIC POLYAMIDE POLYMER LUBRIZOL ADVANCED MAT INC (US) 2025-07-23 EP disclosed
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-08-01 US disclosed
US-20240208192-A1 FILM COMPRISING POLYAMIDE POLYURETHANE LAYER 3M INNOVATIVE PROPERTIES COMPANY 2024-06-27 US disclosed
WO-2024069084-A1 OPTIONALLY SILYLATED IONIC POLYURETHANE(S) BOSTIK SA (FR) 2024-04-04 WO disclosed
EP-4340807-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS Lubrizol Advanced Materials, Inc. (US) 2024-03-27 EP disclosed
US-11597838-B2 Matted polyamide-pud LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-03-07 US disclosed
EP-4132784-A1 FILM COMPRISING POLYAMIDE POLYURETHANE LAYER 3M Innovative Properties Company (US) 2023-02-15 EP disclosed
US-8383713-B2 Hydrolytically stable polyurethane nanocomposites LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-02-26 US disclosed
EP-2467421-A1 HYDROLYTICALLY STABLE POLYURETHANE NANOCOMPOSITES Lubrizol Advanced Materials, Inc. (US) 2012-06-27 EP disclosed
WO-2012068059-A1 POLYMER FOR SURGEONS GLOVES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-24 WO disclosed
WO-2012058534-A1 AQUEOUS CATIONIC POLYURETHANE DISPERSIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-03 WO disclosed
WO-2012058538-A1 FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-03 WO disclosed
EP-2360196-A1 Polyurethane prepolymer and aqueous polyurethane dispersion Stichting Dutch Polymer Institute (NL) 2011-08-24 EP disclosed
WO-2011098272-A2 POLYURETHANE PREPOLYMER AND AQUEOUS POLYURETHANE DISPERSION STICHTING DUTCH POLYMER INSTITUTE (NL) 2011-08-18 WO disclosed
WO-2011022582-A1 HYDROLYTICALLY STABLE POLYURETHANE NANOCOMPOSITES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-02-24 WO disclosed
US-20110046286-A1 Hydrolytically Stable Polyurethane Nanocomposites LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-02-24 US disclosed
US-4496751-A Difunctional furan derivatives THE UNIVERSITY OF MANCHESTER INSTITUTE OF SCIENCE & TECHNOLOGY (GB) 1985-01-29 US disclosed