SCHEMBL845604

SCHEMBL845604

O=C=NCc1ccc(Cc2ccc(CN=C=O)o2)o1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490975 0.93 LMNA (0.35) LMNA
SCHEMBL13884605 0.87 LMNA (0.32) LMNA
SCHEMBL18864324 0.83 LMNA (0.31) LMNA
SCHEMBL30831884 0.82 LMNA (0.30) LMNA
SCHEMBL10993099 0.76 POLB (0.30)
Phthalic Acid SCHEMBL28087427 0.76 ALDH1A1 (0.47) LMNA
Phthalic Acid SCHEMBL28087426 0.76 ALDH1A1 (0.47) LMNA
SCHEMBL825437 0.75
SCHEMBL1054250 0.71
SCHEMBL10993560 0.70 CYP3A4 (0.39) HTTCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4496751-A Difunctional furan derivatives THE UNIVERSITY OF MANCHESTER INSTITUTE OF SCIENCE & TECHNOLOGY (GB) 1985-01-29 US claimed
EP-4340807-B1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MAT INC (US) 2026-01-28 EP disclosed
EP-3233981-B1 PROCESS FOR MAKING A WATERBORNE DISPERSION COMPRISING A CATIONIC POLYAMIDE POLYMER LUBRIZOL ADVANCED MAT INC (US) 2025-07-23 EP disclosed
CN-113939551-B Solvent-borne thermosetting polyamide urethane and/or urea-based coatings 路博润先进材料公司 2024-11-08 CN disclosed
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-08-01 US disclosed
US-20240208192-A1 FILM COMPRISING POLYAMIDE POLYURETHANE LAYER 3M INNOVATIVE PROPERTIES COMPANY 2024-06-27 US disclosed
EP-4340807-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS Lubrizol Advanced Materials, Inc. (US) 2024-03-27 EP disclosed
CN-117355290-A Hair coloring composition for reducing color loss 路博润先进材料公司 2024-01-05 CN disclosed
US-11597838-B2 Matted polyamide-pud LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-03-07 US disclosed
EP-4132784-A1 FILM COMPRISING POLYAMIDE POLYURETHANE LAYER 3M Innovative Properties Company (US) 2023-02-15 EP disclosed
US-20130225755-A1 POLYMERS FOR SURGEONS GLOVES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-08-29 US disclosed
US-20130217286-A1 FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-08-22 US disclosed
US-8383713-B2 Hydrolytically stable polyurethane nanocomposites LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-02-26 US disclosed
EP-2467421-A1 HYDROLYTICALLY STABLE POLYURETHANE NANOCOMPOSITES Lubrizol Advanced Materials, Inc. (US) 2012-06-27 EP disclosed
WO-2012068059-A1 POLYMER FOR SURGEONS GLOVES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-24 WO disclosed
WO-2012058534-A1 AQUEOUS CATIONIC POLYURETHANE DISPERSIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-03 WO disclosed
WO-2012058538-A1 FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-03 WO disclosed
WO-2011022582-A1 HYDROLYTICALLY STABLE POLYURETHANE NANOCOMPOSITES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-02-24 WO disclosed
US-20110046286-A1 Hydrolytically Stable Polyurethane Nanocomposites LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-02-24 US disclosed
US-4496751-A Difunctional furan derivatives THE UNIVERSITY OF MANCHESTER INSTITUTE OF SCIENCE & TECHNOLOGY (GB) 1985-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS TYR, DOT1L, CUTA HTT 826/4885LMNA 810/4885CYP3A4 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.