SCHEMBL490975

SCHEMBL490975

O=C=NCc1ccc(CN=C=O)o1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.32
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13884605 0.93 LMNA (0.32) LMNA
SCHEMBL845604 0.93 HTT (0.33) LMNA
SCHEMBL18864324 0.89 LMNA (0.31) LMNA
SCHEMBL30831884 0.88 LMNA (0.30) LMNA
SCHEMBL10993099 0.82 POLB (0.30) POLB
Phthalic Acid SCHEMBL28087427 0.82 ALDH1A1 (0.47) LMNA
Phthalic Acid SCHEMBL28087426 0.82 ALDH1A1 (0.47) LMNA
SCHEMBL825437 0.80
SCHEMBL1054250 0.76
SCHEMBL109935 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136747-A1 RESIN, MOLDED BODY, OPTICAL MATERIAL, LENS, 2,5-BIS(ISOCYANATOMETHYL)FURAN, AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS, INC. (JP) 2025-05-01 US claimed
CN-118574867-A Resin, molded article, optical material, lens, 2, 5-bis (isocyanatomethyl) furan, and polymerizable composition 三井化学株式会社 2024-08-30 CN claimed
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP claimed
WO-2023167262-A1 RESIN, MOLDED ARTICLE, OPTICAL MATERIAL, LENS, 2,5-BIS(ISOCYANATOMETHYL)FURAN, AND POLYMERIZABLE COMPOSITION 三井化学株式会社 2023-09-07 WO claimed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US claimed
US-11472912-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2022-10-18 US claimed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US claimed
US-11149107-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2021-10-19 US claimed
US-11008418-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2021-05-18 US claimed
US-20200165375-A1 \"Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same\ PPG INDUSTRIES OHIO, INC. 2020-05-28 US claimed
WO-2009005835-A2 ACRYLATED URETHANES, PROCESSES FOR MAKING THE SAME AND CURABLE COMPOSITIONS INCLUDING THE SAME HENKEL CORPORATION (US) 2009-01-08 WO claimed
US-20090012202-A1 Acrylated Urethanes, Processes for Making the Same and Curable Compositions Including the Same HENKEL CORPORATION (US) 2009-01-08 US claimed
EP-2004720-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG Industries Ohio, Inc. (US) 2008-12-24 EP claimed
US-20070225468-A1 Polyurethanes prepared from polyester polyols and/or polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-09-27 US claimed
US-20070173601-A1 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-26 US claimed
US-20070167600-A1 Polyurethanes prepared from polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-19 US claimed
US-20070167601-A1 Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-19 US claimed
US-20070155942-A1 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-07-05 US claimed
US-20070149749-A1 Polyurethanes prepared from polycarbonate polyols, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. 2007-06-28 US claimed
WO-2007070627-A2 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG INDUSTRIES OHIO, INC. (US) 2007-06-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136747-A1 RESIN, MOLDED BODY, OPTICAL MATERIAL, LENS, 2,5-BIS(ISOCYANATOMETHYL)FURAN, AND POLYMERIZABLE COMPOSITION TMT1A, RIF1, RER1 LMNA 2649/4885POLB 4258/4885ACHE 1808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.