SCHEMBL825457

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13451380	0.85	BRD4 (0.47)	BRD4EPHX1L3MBTL1THRBATM
	SCHEMBL8286682	0.84	BRD4 (0.49)	BRD4EPHX1EPHX2L3MBTL1THRB
	SCHEMBL2464935	0.83	L3MBTL1 (0.42)	BRD4ALOX5EPHX2L3MBTL1THRB
	SCHEMBL14827431	0.82	BRD4 (0.51)	BRD4EPHX1L3MBTL1THRBATM
	SCHEMBL771084	0.82	BRD4 (0.48)	BRD4EPHX1L3MBTL1THRBATM
	SCHEMBL1267275	0.82	GAA (0.61)	BRD4L3MBTL1THRBATMGAA
	SCHEMBL25613273	0.81	BRD4 (0.47)	BRD4EPHX1L3MBTL1THRBATM
	SCHEMBL13451670	0.81	BRD4 (0.50)	BRD4EPHX1L3MBTL1THRBATM
	Hydrochloric Acid SCHEMBL28522243	0.81	BRD4 (0.50)	BRD4EPHX1L3MBTL1THRBATM
	SCHEMBL13498638	0.81	BRD4 (0.47)	BRD4EPHX1L3MBTL1THRBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.