Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109233 | 0.85 | KDM4E (0.49) | ALDH1A1MAPTHTTPDCD1CD274 | |
| SCHEMBL9109221 | 0.85 | KDM4E (0.49) | ALDH1A1MAPTHTTPDCD1CD274 | |
| SCHEMBL4986575 | 0.75 | CRBN (0.41) | ALDH1A1MAPTHTTPDCD1CD274 | |
| SCHEMBL8257380 | 0.72 | KDM4E (0.48) | ALDH1A1MAPTPDCD1CD274KDM4E | |
| SCHEMBL9050406 | 0.72 | ALKBH2 (0.40) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL27542501 | 0.72 | ESD (0.43) | ALDH1A1PDCD1CD274KDM4EL3MBTL1 | |
| SCHEMBL28439355 | 0.72 | KMT2A (0.39) | ALDH1A1MAPTHTTPDCD1CD274 | |
| SCHEMBL21853250 | 0.71 | SMN1; SMN2 (0.56) | ALDH1A1MAPTHTTKDM4EL3MBTL1 | |
| SCHEMBL21853236 | 0.71 | SMN1; SMN2 (0.56) | ALDH1A1MAPTHTTKDM4EL3MBTL1 | |
| SCHEMBL1637957 | 0.71 | P2RX7 (0.55) | SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |