Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.47 |
| ▸ | HTR1A | P08908 | 14/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253121 | 0.85 | DRD2 (0.47) | DRD2HTR1AHTR2AMCHR1SLC6A4 | |
| Pardoprunox SCHEMBL805311 | 0.79 | DRD2 (0.58) | DRD2HTR1AHTR2AMCHR1SLC6A4 | |
| Pardoprunox SCHEMBL29358670 | 0.79 | DRD2 (0.58) | DRD2HTR1AHTR2AMCHR1SLC6A4 | |
| Pardoprunox SCHEMBL1584476 | 0.78 | DRD2 (0.57) | DRD2HTR1AHTR2AMCHR1SLC6A4 | |
| Pardoprunox SCHEMBL30730668 | 0.78 | DRD2 (0.57) | DRD2HTR1AHTR2AMCHR1SLC6A4 | |
| Pardoprunox SCHEMBL1584623 | 0.77 | DRD2 (0.56) | DRD2HTR1AHTR2AMCHR1SLC6A4 | |
| SCHEMBL13239009 | 0.76 | DRD2 (0.57) | DRD2HTR1AHTR2AMCHR1SLC6A4 | |
| SCHEMBL1443282 | 0.74 | DRD2 (0.56) | DRD2HTR1AHTR2AMCHR1 | |
| SCHEMBL8261012 | 0.74 | HTR1A (0.48) | DRD2HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL1886136 | 0.73 | DRD2 (0.55) | DRD2HTR1AHTR2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006061379-A1 | PHENYLPIPERAZINE DERIVATIVES WITH A COMBINATION OF PARTIAL DOPAMINE-D2 RECEPTOR AGONISM AND SEROTONIN REUPTAKE INHIBITION | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-06-15 | — | — | WO | disclosed |