Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2872060 | 0.87 | LMNA (0.68) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL18547926 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL1185698 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL4946040 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL9658929 | 0.79 | LMNA (0.61) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL22032826 | 0.75 | LMNA (0.62) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL394951 | 0.75 | L3MBTL1 (0.64) | ALDH1A1TSHRLMNAL3MBTL1MEN1 | |
| SCHEMBL4363906 | 0.74 | ABL1 (0.62) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL1258694 | 0.74 | LMNA (0.54) | ALDH1A1TSHRLMNAGAAMEN1 | |
| SCHEMBL16211057 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006094842-A1 | ACYLATED PIPERIDIHES AS GLYCINE TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-09-14 | — | — | WO | disclosed |