Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658410 | 0.67 | MEN1 (0.42) | MEN1KMT2AKDM4EMAPTBLM | |
| SCHEMBL5940219 | 0.67 | IDO1 (0.79) | MEN1KMT2AKDM4EMAPTBLM | |
| SCHEMBL414700 | 0.66 | S100A4 (0.50) | MEN1KMT2AKDM4EMAPTBLM | |
| 9,10-Phenanthrenequinone SCHEMBL29384320 | 0.61 | MEN1 (1.00) | MEN1KMT2AKDM4EMAPTBLM | |
| 9,10-Phenanthrenequinone SCHEMBL31598775 | 0.61 | MEN1 (1.00) | MEN1KMT2AKDM4EMAPTBLM | |
| 9,10-Phenanthrenequinone SCHEMBL2157215 | 0.61 | MEN1 (1.00) | MEN1KMT2AKDM4EMAPTBLM | |
| 9,10-Phenanthrenequinone SCHEMBL43050 | 0.61 | MEN1 (1.00) | MEN1KMT2AKDM4EMAPTBLM | |
| SCHEMBL939283 | 0.60 | PTPRC (0.63) | MEN1KMT2AKDM4EMAPTBLM | |
| SCHEMBL3369923 | 0.60 | PGR (0.43) | MEN1KMT2AKDM4EMAPTBLM | |
| SCHEMBL29444283 | 0.59 | CDC25B (0.65) | MEN1KMT2AKDM4EMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848432-B1 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | MD BIOALPHA CO LTD (KR) | 2013-07-17 | — | — | EP | disclosed |
| WO-2006088315-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | MD BIOALPHA CO., LTD. (KR) | 2006-08-24 | — | — | WO | disclosed |