Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5810883 | 0.84 | HSD11B1 (0.43) | MAOAMAOBALDH1A1KDM1A | |
| SCHEMBL23647570 | 0.84 | MEN1 (0.48) | MAOAMAOBCHRM2ALDH1A1CYP46A1 | |
| SCHEMBL3833018 | 0.81 | AVPR1A (0.62) | OPRM1OPRL1AVPR1ACYP46A1CYP3A4 | |
| SCHEMBL3485621 | 0.80 | AVPR1A (0.44) | OPRM1OPRL1AVPR1ACYP2D6CHRM2 | |
| SCHEMBL3592463 | 0.80 | OPRD1 (0.54) | MAOAMAOB | |
| SCHEMBL20137787 | 0.79 | CYP46A1 (0.46) | OPRM1CHRM2ALDH1A1CYP46A1MAPK1 | |
| SCHEMBL20148005 | 0.79 | MAOA (0.70) | MAOAMAOBOPRM1OPRL1ALDH1A1 | |
| SCHEMBL5994665 | 0.79 | ALDH1A1 (0.62) | ALDH1A1NPC1 | |
| SCHEMBL1318340 | 0.78 | MAOA (1.00) | MAOAMAOBOPRM1OPRL1KDM1A | |
| SCHEMBL8267929 | 0.77 | MAOA (0.68) | MAOAMAOBOPRM1OPRL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |