Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | ARG1 | P05089 | 5/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.30 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296699 | 0.95 | CYP2C19 (0.41) | PLGPLATLMNAKDM1ANCF1 | |
| SCHEMBL1970445 | 0.93 | PLG (0.40) | PLGPLATLMNAKDM1ANCF1 | |
| SCHEMBL1970098 | 0.86 | PLG (0.35) | PLGPLATLMNAKDM1ANCF1 | |
| SCHEMBL1969857 | 0.82 | HTR2A (0.39) | KDM1ACYP2D6ARG1CYP2C19HRH1 | |
| SCHEMBL1968493 | 0.82 | CYP4F2 (0.37) | PLGPLATLMNAKDM1ANCF1 | |
| SCHEMBL22629578 | 0.80 | HTR7 (0.40) | KDM1ACYP2C19 | |
| SCHEMBL3294534 | 0.79 | ARG1 (0.41) | CYP2D6ARG1CYP2C19HRH1 | |
| SCHEMBL1970718 | 0.79 | CYP4F2 (0.40) | PLGPLATLMNAKDM1ANCF1 | |
| SCHEMBL5325486 | 0.75 | CYP2C19 (0.48) | LMNAKDM1ACYP2C19HRH1 | |
| SCHEMBL3589272 | 0.75 | CYP4F2 (0.34) | NCF1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006090279-A1 | OXYINDOLE DERIVATIVES AS 5HT4 RECEPTOR AGONISTS | PFIZER JAPAN INC. (JP) | 2006-08-31 | — | — | WO | disclosed |