Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923342 | 0.81 | METAP2 (0.35) | METAP2 | |
| SCHEMBL15871759 | 0.75 | ALDH1A1 (0.35) | METAP2 | |
| SCHEMBL12593191 | 0.72 | SIGMAR1 (0.37) | METAP2 | |
| SCHEMBL7514151 | 0.72 | SIGMAR1 (0.37) | METAP2 | |
| SCHEMBL7519673 | 0.68 | ALDH1A1 (0.39) | — | |
| SCHEMBL7519834 | 0.66 | ALDH1A1 (0.40) | — | |
| SCHEMBL7519855 | 0.63 | GRM2 (0.41) | — | |
| SCHEMBL22131508 | 0.63 | ALDH1A1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL10421626 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL7519868 | 0.61 | CYP1A2 (0.41) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065277-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2006-06-22 | — | — | WO | disclosed |