Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271710 | 0.81 | ACKR3 (0.41) | MEN1KMT2ARAB9ASMN1; SMN2POLB | |
| SCHEMBL14349266 | 0.79 | ACACB (0.43) | MEN1KMT2ARAB9AACACBSMN1; SMN2 | |
| SCHEMBL4234552 | 0.78 | SMN1; SMN2 (0.48) | MEN1KMT2ARAB9AACACBSMN1; SMN2 | |
| SCHEMBL12490134 | 0.77 | FAAH (0.47) | MEN1KMT2ARAB9ASMN1; SMN2POLB | |
| SCHEMBL14375996 | 0.76 | CKS1B (0.56) | MEN1KMT2ARAB9AACACBSMN1; SMN2 | |
| SCHEMBL14349357 | 0.76 | CKS1B (0.56) | MEN1KMT2ARAB9AACACBSMN1; SMN2 | |
| SCHEMBL4227209 | 0.74 | NOTUM (0.44) | RAB9ALMNA | |
| SCHEMBL4227170 | 0.72 | SMN1; SMN2 (0.51) | MEN1KMT2ARAB9ASMN1; SMN2POLB | |
| SCHEMBL8271752 | 0.72 | LMNA (0.46) | RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL12506166 | 0.72 | GPR119 (0.51) | MEN1KMT2ARAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006017409-A2 | 1,3-DISUBSTITUTED HETEROARYL NMDA/NR2B ANTAGONISTS | MERCK & CO., INC. (US) | 2006-02-16 | — | — | WO | disclosed |