Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12134775 | 0.95 | KMT2A (0.60) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL9882908 | 0.95 | KMT2A (0.60) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL230688 | 0.90 | KMT2A (0.72) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL31031901 | 0.90 | KMT2A (0.72) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL29468684 | 0.90 | KMT2A (0.72) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL1660910 | 0.89 | KMT2A (0.74) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL29401182 | 0.87 | KMT2A (0.77) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL29458423 | 0.87 | KMT2A (0.77) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL887559 | 0.87 | KMT2A (0.77) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL6889085 | 0.87 | KMT2A (0.77) | KMT2AEPHX2CASP3FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006009645-A1 | METHODS OF USING MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR | TRANZYME PHARMA, INC. (US) | 2006-01-26 | — | — | WO | disclosed |