SCHEMBL887559

SCHEMBL887559

O=C(NCCCCCCO)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.77

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.77
EPHX2 P34913 1/20 0.50
FABP7 O15540 1/20 0.43
FABP5 Q01469 1/20 0.43
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43
CASP3 P42574 2/20 0.42
DOT1L Q8TEK3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401182 1.00 KMT2A (0.77) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL6889085 1.00 KMT2A (0.77) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL29458423 1.00 KMT2A (0.77) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL1660910 0.99 KMT2A (0.74) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL230688 0.94 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29468684 0.94 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31031901 0.94 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL793384 0.94 KMT2A (0.85) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL163534 0.89 KMT2A (0.67) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL15160681 0.88 KMT2A (0.75) KMT2AEPHX2FABP7FABP5TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12467085-B2 High accuracy nanopore-based single molecule sequencing by synthesis with tagged nucleotides THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-11-11 US disclosed
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 US disclosed
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 US disclosed
US-20240400684-A1 ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-12-05 US disclosed
US-20240209432-A1 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2024-06-27 US disclosed
EP-4303314-A2 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION F. Hoffmann-La Roche AG (CH) 2024-01-10 EP disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 US disclosed
US-11739378-B2 Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection Roche Sequencing Solutions, Inc. (US) 2023-08-29 US disclosed
US-20230167450-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-06-01 US disclosed
US-20230158156-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-05-25 US disclosed
US-20040253181-A1 Novel compositions magnetic particles covered with gem-bisphosphonate derivatives GUERBET (FR) 2004-12-16 US disclosed
WO-2004058275-A2 COMPOSITIONS OF MAGNETIC PARTICLES COVERED WITH GEM-BISPHOSPHONATE DERIVATIVES GUERBET (FR) 2004-07-15 WO disclosed
EP-0643778-B1 ENCODED COMBINATORIAL CHEMICAL LIBRARIES SCRIPPS RESEARCH INST (US) 2000-05-31 EP disclosed
EP-0647133-A4 COMPOSITIONS AND METHODS FOR ENHANCED DRUG DELIVERY. AFFYMAX TECH NV (AN) 1997-10-29 EP disclosed
US-5607691-A IONTOPHORESIS AFFYMAX TECHNOLOGIES N.V. (GB) 1997-03-04 US disclosed
EP-0643778-A4 ENCODED COMBINATORIAL CHEMICAL LIBRARIES. SCRIPPS RESEARCH INST (US) 1995-09-20 EP disclosed
EP-0647133-A1 COMPOSITIONS AND METHODS FOR ENHANCED DRUG DELIVERY AFFYMAX TECHNOLOGIES N.V. (AN) 1995-04-12 EP disclosed
EP-0643778-A1 ENCODED COMBINATORIAL CHEMICAL LIBRARIES THE SCRIPPS RESEARCH INSTITUTE (US) 1995-03-22 EP disclosed
WO-1993025197-A1 COMPOSITIONS AND METHODS FOR ENHANCED DRUG DELIVERY AFFYMAX TECHNOLOGIES N.V. (AN) 1993-12-23 WO disclosed
WO-1993020242-A1 ENCODED COMBINATORIAL CHEMICAL LIBRARIES THE SCRIPPS RESEARCH INSTITUTE (US) 1993-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739378-B2 Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection NPPA, ANPEP, TENT4A KMT2A 3667/4885EPHX2 4673/4885FABP7 1315/4885
US-20230158156-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, SNRPE, DDX21 KMT2A 3463/4885EPHX2 1615/4885FABP7 820/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 KMT2A 2167/4885EPHX2 2080/4885FABP7 1242/4885
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885
US-20240209432-A1 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION NPPA, ANPEP, TENT4A KMT2A 3667/4885EPHX2 4673/4885FABP7 1315/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.