SCHEMBL1660910

SCHEMBL1660910

O=C(NCCCCO)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.74
EPHX2 P34913 1/20 0.51
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44
CASP3 P42574 2/20 0.43
DOT1L Q8TEK3 1/20 0.42
GBA1 P04062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401182 0.99 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL6889085 0.99 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL887559 0.99 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29458423 0.99 KMT2A (0.77) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL230688 0.96 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31031901 0.96 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29468684 0.96 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL793384 0.93 KMT2A (0.85) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL163534 0.90 KMT2A (0.67) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL17971325 0.89 KMT2A (0.74) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4681777-A2 PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF XWPharma Ltd. (KY) 2026-01-21 EP disclosed
EP-3737665-B1 PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF XWPHARMA LTD (KY) 2026-01-07 EP disclosed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 US disclosed
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 US disclosed
US-20240400684-A1 ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-12-05 US disclosed
US-20240398962-A1 DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY (CZ) 2024-12-05 US disclosed
WO-2024040169-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS THE UNIVERSITY OF CHICAGO (US) 2024-02-22 WO disclosed
EP-4322961-A1 DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF The Johns Hopkins University (US) 2024-02-21 EP disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 US disclosed
US-20070112008-A1 Saframycins, analogues and uses thereof MYERS ANDREW G 2007-05-17 US disclosed
US-20070112008-A1 Saframycins, analogues and uses thereof MYERS ANDREW G 2007-05-17 US disclosed
US-7122549-B2 Saframycins, analogues and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-10-17 US disclosed
WO-2006097320-A2 MACROMOLECULAR NUCLEOTIDE LINKS AND METHODS FOR THEIR USE GENOVOXX GMBH (DE) 2006-09-21 WO disclosed
US-6809099-B2 FOR THERAPY OF CANCER PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2004-10-26 US disclosed
US-20040204419-A1 Saframycins, analogues and uses thereof MYERS ANDREW G (US) 2004-10-14 US disclosed
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis ARIAD PHARMACEUTICALS INC. 2004-01-22 US disclosed
EP-1339713-A2 SAFRAMYCINS, ANALOGUES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2003-09-03 EP disclosed
US-20030008873-A1 Saframycins, analogues and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-09 US disclosed
WO-2002040477-A2 SAFRAMYCINS, ANALOGUES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2002-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204419-A1 Saframycins, analogues and uses thereof MYC, MAN1B1, MRPS18A KMT2A 3777/4885EPHX2 3737/4885FABP7 2566/4885
US-20070112008-A1 Saframycins, analogues and uses thereof MYC, MAN1B1, MRPS18A KMT2A 3796/4885EPHX2 3637/4885FABP7 2542/4885
US-20030008873-A1 Saframycins, analogues and uses thereof MYC, MAN1B1, MRPS18A KMT2A 3777/4885EPHX2 3737/4885FABP7 2566/4885
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis SRC, CTTN, YES1 KMT2A 1865/4885EPHX2 4197/4885FABP7 4354/4885
US-20240398962-A1 DENDRIMER-GLUTAMINE ANTAGONIST CONJUGATES AND METHODS OF USE THEREOF GLUL, GLS, GRM2 KMT2A 398/4885EPHX2 4017/4885FABP7 363/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 KMT2A 2167/4885EPHX2 2080/4885FABP7 1242/4885
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.