SCHEMBL6889085

SCHEMBL6889085

O=C(NCCCCCO)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.77

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.77
EPHX2 P34913 1/20 0.50
FABP7 O15540 1/20 0.43
FABP5 Q01469 1/20 0.43
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43
CASP3 P42574 2/20 0.42
DOT1L Q8TEK3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401182 1.00 KMT2A (0.77) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL29458423 1.00 KMT2A (0.77) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL887559 1.00 KMT2A (0.77) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL1660910 0.99 KMT2A (0.74) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL230688 0.94 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29468684 0.94 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL31031901 0.94 KMT2A (0.72) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL793384 0.94 KMT2A (0.85) KMT2AEPHX2FABP7FABP5TLR2
SCHEMBL163534 0.89 KMT2A (0.67) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL15160681 0.88 KMT2A (0.75) KMT2AEPHX2FABP7FABP5TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 US disclosed
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 US disclosed
US-20240400684-A1 ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-12-05 US disclosed
EP-3743517-B1 SEQUENCING ADDITIVE QIAGEN SCIENCES LLC (US) 2024-03-06 EP disclosed
WO-2024040169-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS THE UNIVERSITY OF CHICAGO (US) 2024-02-22 WO disclosed
US-11821032-B2 DNA sequencing reaction additive IsoPlexis Corporation (US) 2023-11-21 US disclosed
US-20230340583-A1 DNA SEQUENCING REACTION ADDITIVE IsoPlexis Corporation 2023-10-26 US disclosed
US-20230330245-A1 ANTIBODY-EXATECAN CONJUGATES SYNAFFIX B.V. (NL) 2023-10-19 US disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 US disclosed
US-20140206595-A1 CLEANING MIXTURE FOR THE REMOVAL OR AVOIDANCE OF INSECT DEPOSITS ON SURFACES EADS DEUTSCHLAND GMBH (DE) 2014-07-24 US disclosed
EP-2746378-A1 Cleaning mixture for removing or preventing deposits from insects on surfaces EADS Deutschland GmbH (DE) 2014-06-25 EP disclosed
US-20140134193-A1 SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION PFIZER INC. (US) 2014-05-15 US disclosed
US-20140134193-A1 SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION PFIZER INC. (US) 2014-05-15 US disclosed
US-20140134193-A1 SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION PFIZER INC. (US) 2014-05-15 US disclosed
WO-2014068443-A1 SPLICEOSTATIN ANALOGS PFIZER INC. (US) 2014-05-08 WO disclosed
WO-2013170077-A2 V1A RECEPTOR AGONISTS FERRING B.V. (NL) 2013-11-14 WO disclosed
WO-2013116682-A1 MACROCYCLIC COMPOUNDS FOR MODULATING IL-17 ENSEMBLE THERAPEUTICS CORPORATION (US) 2013-08-08 WO disclosed
US-6764768-B2 SELF ASSEMBLING MONOLAYERS OF ALKANETHIOLATES ARCH DEVELOPMENT CORPORATION 2004-07-20 US disclosed
US-20020119305-A1 Controlled release composition ARCH DEVELOPMENT CORPORATION 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140134193-A1 SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION SF3B5, SNRPA1, SF3B1 KMT2A 1507/4885EPHX2 3793/4885FABP7 3357/4885
US-20230330245-A1 ANTIBODY-EXATECAN CONJUGATES ERBB3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, IL23R KMT2A 1164/4885EPHX2 1524/4885FABP7 4099/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 KMT2A 2167/4885EPHX2 2080/4885FABP7 1242/4885
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885
US-11821032-B2 DNA sequencing reaction additive RNGTT, NSUN2, NT5C3B KMT2A 2077/4885EPHX2 2123/4885FABP7 3838/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE KMT2A 3085/4885EPHX2 1836/4885FABP7 877/4885
US-20230340583-A1 DNA SEQUENCING REACTION ADDITIVE RNGTT, NSUN2, NT5C3B KMT2A 2077/4885EPHX2 2123/4885FABP7 3838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.