Broxaterol

Broxaterol

SCHEMBL82745

CC(C)(C)NCC(O)c1cc(Br)no1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 9/20 0.46
LMNA P02545 4/20 0.46
TSHR P16473 2/20 0.46
CYP3A4 P08684 2/20 0.46
CASP7 P55210 2/20 0.46
KMT2A Q03164 2/20 0.46
HIF1A Q16665 2/20 0.46
CYP2C9 P11712 1/20 0.46
ADRB1 P08588 7/20 0.44
ADRB3 P13945 5/20 0.44
HTR1A P08908 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRK1 P41145 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KDM4E B2RXH2 2/20 0.41
CASP1 P29466 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Broxaterol SCHEMBL8845005 0.98 ADRB2 (0.45) ADRB2LMNATSHRCYP3A4CASP7
SCHEMBL4538650 0.79 ADRB2 (0.54) ADRB2LMNATSHRCYP3A4KMT2A
Carbuterol SCHEMBL18047896 0.78 ADRB2 (0.45) ADRB2TSHRKMT2AHIF1AADRB1
SCHEMBL8879834 0.75 ADRB2 (0.44) ADRB2LMNAADRB1ADRB3
SCHEMBL6074317 0.75 ADRB2 (0.40) ADRB2ADRB1ADRB3
SCHEMBL8129014 0.75 ADRB2 (0.40) ADRB2ADRB1ADRB3
SCHEMBL10341872 0.73 ADRB2 (0.45) ADRB2ADRB1ADRB3
SCHEMBL6074550 0.72 ADRB2 (0.39) ADRB2LMNATSHRCYP3A4KMT2A
SCHEMBL10614263 0.69 LMNA (0.66) ADRB2LMNATSHRCYP3A4CASP7
Hydrochloric Acid SCHEMBL10614258 0.68 LMNA (0.64) ADRB2LMNATSHRCYP3A4CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3100 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017878-A1 USE OF NADOLOL TO TREAT CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY BLOCKAGE OF THE ARRESTIN-2 PATHWAY CHRONIC AIRWAY THERAPEUTICS LTD (AU) 2025-01-16 US claimed
US-20240398729-A1 Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders DUKE UNIVERSITY (US) 2024-12-05 US claimed
EP-4126138-B1 AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS INVOX BELGIUM NV (BE) 2024-10-16 EP claimed
WO-2024189434-A1 USE OF NADOLOL TO TREAT PULMONARY SYMPTOMS ASSOCIATED WITH INFECTIONS WITH SARS-CoV-2 CHRONIC AIRWAY THERAPEUTICS LIMITED (AU) 2024-09-19 WO claimed
EP-1962797-B2 POWDER COMPOSITIONS FOR INHALATION JAGOTEC AG (CH) 2024-05-29 EP claimed
EP-4329849-A1 INHALER 3D Engineering Design Limited (GB) 2024-03-06 EP claimed
EP-4304717-A1 USE OF NADOLOL TO TREAT CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY BLOCKAGE OF THE ARRESTIN-2 PATHWAY Chronic Airway Therapeutics Limited (AU) 2024-01-17 EP claimed
US-20230158028-A1 COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-05-25 US claimed
EP-4132914-A1 COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION The Regents of the University of California (US) 2023-02-15 EP claimed
EP-4126138-A1 AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS Softhale NV (BE) 2023-02-08 EP claimed
EP-0486959-B1 Pharmaceutical composition of microparticles with controlled release and process of preparing it VECTORPHARMA INT (IT) 1996-08-28 EP claimed
US-5536508-A BIODEGRADABLE POLYMER AND POLYSACCHARIDE GEL AND BIOADHESIVE WITH DRUG VECTORPHARMA INTERNATIONAL S.P.A. (IT) 1996-07-16 US claimed
WO-1996019198-A1 AEROSOL DRUG FORMULATIONS ASTRA AKTIEBOLAG (SE) 1996-06-27 WO claimed
EP-0717616-A1 PROCESS FOR CONDITIONING SUBSTANCES Astra Aktiebolag (SE) 1996-06-26 EP claimed
EP-0526862-B1 Solid pharmaceutical compositions for oral administration with prolonged gastric residence VECTORPHARMA INT (IT) 1996-02-14 EP claimed
WO-1995005805-A1 PROCESS FOR CONDITIONING SUBSTANCES ASTRA AKTIEBOLAG (SE) 1995-03-02 WO claimed
US-5312627-A Polymer matrix with drugs with bronchodilator agents ZAMBON GROUP S.P.A. (IT) 1994-05-17 US claimed
EP-0523537-A1 Transdermal therapeutic system for the administration of drugs having bronchodilating activity ZAMBON GROUP S.p.A. (IT) 1993-01-20 EP claimed
EP-0486959-A1 Pharmaceutical composition of microparticles with controlled release and process of preparing it VECTORPHARMA INTERNATIONAL S.P.A. (IT) 1992-05-27 EP claimed
EP-0016255-B1 ISOXAZOLE DERIVATIVE, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME ZAMBON S.p.A. (IT) 1983-09-28 EP claimed