⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825005 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL29854261 | 0.68 | TRPA1 (0.41) | — | |
| SCHEMBL160662 | 0.67 | ALOX15 (0.31) | — | |
| SCHEMBL30624470 | 0.67 | ALOX15 (0.31) | — | |
| SCHEMBL255497 | 0.64 | — | — | |
| SCHEMBL44015 | 0.63 | S100A4 (0.39) | — | |
| SCHEMBL4096261 | 0.61 | TSHR (0.32) | — | |
| SCHEMBL5320061 | 0.61 | CYP1A2 (0.31) | — | |
| SCHEMBL30625726 | 0.61 | TSHR (0.32) | — | |
| SCHEMBL31001735 | 0.60 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120822-B2 | Tricyclic antibiotics | BASILEA PHARMACEUTICA AG (CH) | 2015-09-01 | — | — | US | claimed |
| US-20150072975-A1 | TRICYCLIC ANTIBIOTICS | BASILEA PHARMACEUTICA AG | 2015-03-12 | — | — | US | claimed |
| US-8716280-B2 | Bicyclic antibiotics | BASILEA PHARMACEUTICA AG (CH) | 2014-05-06 | — | — | US | claimed |
| EP-0227982-A1 | 1-H-Pyrido[3,2-b][1,4]thiazines | BAYER AG (DE) | 1987-07-08 | — | — | EP | claimed |
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3717478-A1 | ENDOPARASITIC DEPSIPEPTIDES | Zoetis Services LLC (US) | 2020-10-07 | — | — | EP | disclosed |
| US-20200282016-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2020-09-10 | — | — | US | disclosed |
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
| EP-0877748-B1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | UNIV LIEGE (BE) | 2004-11-03 | — | — | EP | disclosed |
| CN-1208418-A | Pyrido-1, 2, 4-thiadiazine and pyrido-1, 4-thiazine derivatives, preparation method and application thereof | NOVO NORDISK AS (DK) | 1999-02-17 | — | — | CN | disclosed |
| EP-0877748-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-18 | — | — | EP | disclosed |
| US-5792764-A | ENDOCRINE DISORDERS ESPECIALLY AS A K(ATP)-CHANNEL MODULATOR | NOVO NORDISK A/S (DK) | 1998-08-11 | — | — | US | disclosed |
| US-5792764-A | ENDOCRINE DISORDERS ESPECIALLY AS A K(ATP)-CHANNEL MODULATOR | NOVO NORDISK A/S (DK) | 1998-08-11 | — | — | US | disclosed |
| US-5792764-A | ENDOCRINE DISORDERS ESPECIALLY AS A K(ATP)-CHANNEL MODULATOR | NOVO NORDISK A/S (DK) | 1998-08-11 | — | — | US | disclosed |
| WO-1997026264-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |
| US-4784997-A | INHIBITORS OF LIPOXYGENASE, ANTIINFLAMMMATORY AGENTS, ANTIALLERGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0227982-A1 | 1-H-Pyrido[3,2-b][1,4]thiazines | BAYER AG (DE) | 1987-07-08 | — | — | EP | disclosed |