Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.40 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827826 | 1.00 | NT5E (0.47) | NT5EPOLBLMNATSHRKMT2A | |
| SCHEMBL9332856 | 0.89 | LMNA (0.52) | POLBLMNATSHRKMT2ACYP2D6 | |
| SCHEMBL9332848 | 0.89 | LMNA (0.52) | POLBLMNATSHRKMT2ACYP2D6 | |
| SCHEMBL24804649 | 0.89 | LMNA (0.52) | POLBLMNATSHRKMT2ACYP2D6 | |
| SCHEMBL29865166 | 0.89 | LMNA (0.52) | POLBLMNATSHRKMT2ACYP2D6 | |
| SCHEMBL8002809 | 0.87 | CYP3A4 (0.46) | POLBLMNATSHRKMT2ACYP2D6 | |
| SCHEMBL8699184 | 0.83 | TSHR (0.50) | POLBLMNATSHRKMT2ACYP2D6 | |
| SCHEMBL8699189 | 0.83 | TSHR (0.50) | POLBLMNATSHRKMT2ACYP2D6 | |
| SCHEMBL7028051 | 0.82 | TSHR (0.54) | LMNATSHRKMT2ACYP2D6P4HB | |
| SCHEMBL1527155 | 0.82 | TSHR (0.54) | LMNATSHRKMT2ACYP2D6P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143072-B2 | System for detecting nanoparticles using modulated surface plasmon resonance | THE UNIVERSITY OF TOLEDO (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100164489-A1 | System for Detecting Nanoparticles Using Modulated Surface Plasmon Resonance | THE UNIVERSITY OF TOLEDO (US) | 2010-07-01 | — | — | US | disclosed |