Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714422 | 0.85 | MAPT (0.46) | MAPTALDH1A1HPGDCYP3A4CYP2C9 | |
| SCHEMBL8279469 | 0.76 | HSD17B1 (0.52) | MAPTHSD17B1HSD17B2HTTL3MBTL1 | |
| SCHEMBL8278260 | 0.74 | MAOA (0.51) | MAPTALDH1A1MAOAMAOBMEN1 | |
| SCHEMBL5798049 | 0.71 | MAPT (0.54) | MAPTALDH1A1HTTMAOAMAOB | |
| SCHEMBL4879094 | 0.71 | KDM4E (0.44) | MAPTHPGDHTTNPSR1L3MBTL1 | |
| SCHEMBL7354642 | 0.70 | CA12 (0.55) | MAPTALDH1A1HPGDCYP3A4CYP2C9 | |
| SCHEMBL4445490 | 0.69 | RAB9A (0.54) | MAPTALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL17244572 | 0.64 | CYP2A6 (0.49) | MAPTALDH1A1HPGDMAOAMAOB | |
| SCHEMBL19019161 | 0.63 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27949258 | 0.63 | CYP2A6 (0.52) | MAPTALDH1A1HPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |