Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 5/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180844 | 0.82 | TDP1 (0.70) | MAPTTDP1LMNAALDH1A1GFER | |
| SCHEMBL15678983 | 0.81 | KEAP1 (0.66) | MAPTALDH1A1MAPK1CA1CA2 | |
| SCHEMBL5718766 | 0.81 | ALDH1A1 (0.73) | MAPTTDP1LMNAALDH1A1GFER | |
| SCHEMBL8278258 | 0.79 | PGR (0.70) | MAPTLMNAALDH1A1MAPK1HTT | |
| SCHEMBL4884368 | 0.79 | TDP1 (0.65) | MAPTTDP1LMNAALDH1A1GFER | |
| SCHEMBL8281114 | 0.78 | TDP1 (0.64) | MAPTTDP1LMNAALDH1A1GFER | |
| SCHEMBL8281131 | 0.78 | TDP1 (0.64) | MAPTTDP1LMNAALDH1A1GFER | |
| SCHEMBL14018727 | 0.78 | MAPT (0.64) | MAPTTDP1LMNAALDH1A1GFER | |
| SCHEMBL8279469 | 0.77 | HSD17B1 (0.52) | MAPTLMNACA2HTTPGR | |
| SCHEMBL4878626 | 0.77 | MEN1 (0.70) | MAPTTDP1LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |