Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.77 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.62 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.56 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633919 | 0.82 | GABRA1 (0.72) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL12335543 | 0.81 | GABRA1 (0.70) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL13211036 | 0.80 | GABRA1 (0.69) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL12334565 | 0.80 | GABRA1 (0.68) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL13633888 | 0.79 | GABRA1 (0.67) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL2197561 | 0.78 | GABRA1 (0.59) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL6627698 | 0.77 | GABRA1 (0.65) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL788220 | 0.76 | PFKFB3 (1.00) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL13633870 | 0.76 | PFKFB3 (0.70) | GABRA1PFKFB3PFKFB4CCKBRMMP8 | |
| SCHEMBL5692826 | 0.76 | GABRA1 (0.64) | GABRA1PFKFB3PFKFB4CCKBRMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255169-A1 | 4'-Fluoro-biphenyl-3-sulfonic acid benzo[1,3]dioxol-5-ylamide, for example; for use as an alpha 2 beta 1 integrin I domain inhibitor; use as a medicament for treating thrombosis and cancer spread | BIOTIE THERAPIES CORPORATION (FI) | 2008-10-16 | — | — | US | disclosed |
| US-20080255169-A1 | 4'-Fluoro-biphenyl-3-sulfonic acid benzo[1,3]dioxol-5-ylamide, for example; for use as an alpha 2 beta 1 integrin I domain inhibitor; use as a medicament for treating thrombosis and cancer spread | BIOTIE THERAPIES CORPORATION (FI) | 2008-10-16 | — | — | US | disclosed |
| WO-2005090298-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255169-A1 | 4'-Fluoro-biphenyl-3-sulfonic acid benzo[1,3]dioxol-5-ylamide, for example; for use as an alpha 2 beta 1 integrin I domain inhibitor; use as a medicament for treating thrombosis and cancer spread | NR1I2, ITGA2, ITGB2 | GABRA1 70/4885PFKFB3 2386/4885PFKFB4 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.