Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.79 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PON1 | P27169 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vadimezan SCHEMBL29356696 | 0.88 | STING1 (1.00) | GLASTING1KDM4EMCL1PON1 | |
| Vadimezan SCHEMBL29363732 | 0.88 | STING1 (1.00) | GLASTING1KDM4EMCL1PON1 | |
| Vadimezan SCHEMBL111183 | 0.88 | STING1 (1.00) | GLASTING1KDM4EMCL1PON1 | |
| Vadimezan SCHEMBL4282923 | 0.87 | STING1 (0.97) | GLASTING1KDM4EMCL1PON1 | |
| Vadimezan SCHEMBL4282930 | 0.87 | STING1 (0.97) | GLASTING1KDM4EMCL1PON1 | |
| SCHEMBL13025119 | 0.85 | GLA (0.81) | GLASTING1KDM4EMCL1PON1 | |
| SCHEMBL23900884 | 0.85 | GLA (0.75) | GLASTING1KDM4EMCL1PON1 | |
| SCHEMBL12677568 | 0.85 | GLA (0.75) | GLASTING1KDM4EMCL1PON1 | |
| SCHEMBL19209663 | 0.84 | GLA (0.79) | GLASTING1KDM4EMCL1PON1 | |
| SCHEMBL20845573 | 0.84 | GLA (0.79) | GLASTING1KDM4EMCL1PON1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216497-A1 | Ferritin Proteins | SANOFI (FR) | 2024-07-04 | — | — | US | disclosed |
| US-11904009-B2 | Ferritin proteins | SANOFI (FR) | 2024-02-20 | — | — | US | disclosed |
| US-20230277619-A1 | ANTIGENIC EPSTEIN BARR VIRUS POLYPEPTIDES | SANOFI (FR) | 2023-09-07 | — | — | US | disclosed |
| US-20120129895-A1 | METHODS OF TREATMENT | NOVARTIS AG (CH) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216497-A1 | Ferritin Proteins | FTH1, TFRC, SLC40A1 | GLA 3085/4885STING1 270/4885KDM4E 4549/4885 |
| US-11904009-B2 | Ferritin proteins | FTH1, TFRC, SLC40A1 | GLA 3085/4885STING1 270/4885KDM4E 4549/4885 |
| US-20230277619-A1 | ANTIGENIC EPSTEIN BARR VIRUS POLYPEPTIDES | EBNA1BP2, FTH1, CD2BP2 | GLA 1611/4885STING1 693/4885KDM4E 3054/4885 |
| US-20120129895-A1 | METHODS OF TREATMENT | BIRC5, BIRC3, XIAP | GLA 826/4885STING1 2759/4885KDM4E 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.