Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8244941 | 0.83 | MGLL (0.40) | ALDH1A1GAAMMP2ANPEPAGTR2 | |
| SCHEMBL12600876 | 0.81 | F13A1 (0.41) | ALDH1A1GAAMMP2ANPEPMGLL | |
| SCHEMBL7850110 | 0.81 | F13A1 (0.41) | F13A1TGM2 | |
| SCHEMBL12142687 | 0.81 | F13A1 (0.41) | F13A1TGM2 | |
| SCHEMBL14569797 | 0.81 | F13A1 (0.41) | F13A1TGM2 | |
| SCHEMBL14583933 | 0.81 | F13A1 (0.41) | F13A1TGM2 | |
| SCHEMBL12141232 | 0.80 | THRB (0.36) | GAAMMP2ANPEPAGTR2MGLL | |
| SCHEMBL14073406 | 0.78 | AGTR2 (0.40) | ALDH1A1GAAMMP2ANPEPAGTR2 | |
| SCHEMBL16313133 | 0.73 | MGLL (0.35) | ALDH1A1GAAMGLLF13A1TGM2 | |
| SCHEMBL8280797 | 0.71 | CTSV (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087731-A1 | SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-09-22 | — | — | WO | disclosed |