Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.73 |
| ▸ | CHRM3 | P20309 | 20/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828200 | 1.00 | ADRB2 (0.73) | ADRB2CHRM3CHRM2 | |
| SCHEMBL384382 | 0.94 | ADRB2 (0.82) | ADRB2CHRM3CHRM2 | |
| SCHEMBL384381 | 0.94 | ADRB2 (0.82) | ADRB2CHRM3CHRM2 | |
| SCHEMBL3431094 | 0.94 | ADRB2 (0.82) | ADRB2CHRM3CHRM2 | |
| SCHEMBL4282074 | 0.92 | ADRB2 (0.73) | ADRB2CHRM3CHRM2 | |
| SCHEMBL829417 | 0.92 | ADRB2 (0.73) | ADRB2CHRM3CHRM2 | |
| SCHEMBL827897 | 0.91 | ADRB2 (0.88) | ADRB2CHRM3CHRM2 | |
| SCHEMBL827898 | 0.91 | ADRB2 (0.88) | ADRB2CHRM3CHRM2 | |
| SCHEMBL19088806 | 0.89 | ADRB2 (0.67) | ADRB2CHRM3CHRM2 | |
| SCHEMBL828201 | 0.89 | ADRB2 (0.66) | ADRB2CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143277-B2 | Method of using compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity | THERAVANCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20090239904-A1 | COMPOUNDS HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | THERAVANCE, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-7569586-B2 | Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity | THERAVANCE, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-20060035933-A1 | Compounds having beta adrenergic receptor agonist and muscarinic receptor antagonist activity | THERAVANCE BIOPHARMA R&D IP, LLC | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035933-A1 | Compounds having beta adrenergic receptor agonist and muscarinic receptor antagonist activity | ADRA2B, ADRB1, ADRA1B | ADRB2 4/4885CHRM3 12/4885CHRM2 8/4885 |
| US-20090239904-A1 | COMPOUNDS HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ADRA2B, ADRB2, ADRB1 | ADRB2 2/4885CHRM3 12/4885CHRM2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.