Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246405 | 0.84 | CASP1 (0.52) | CASP1CASP7HSD17B10HSD17B1MAOA | |
| SCHEMBL8253223 | 0.84 | NPC1 (0.61) | CASP1CASP7HSD17B10HSD17B1MAOA | |
| SCHEMBL10518407 | 0.80 | CASP1 (0.52) | CASP1CASP7HSD17B10HSD17B1MAOA | |
| SCHEMBL1275273 | 0.78 | SRD5A2 (0.66) | CASP1CASP7HSD17B10HSD17B1MAOA | |
| SCHEMBL29431442 | 0.78 | SRD5A2 (0.66) | CASP1CASP7HSD17B10HSD17B1MAOA | |
| SCHEMBL14344095 | 0.77 | ALDH1A1 (0.45) | HSD17B1NPC1MAPTRAB9A | |
| SCHEMBL9944563 | 0.76 | CASP1 (0.52) | CASP1CASP7HSD17B10HSD17B1MAOA | |
| SCHEMBL1091518 | 0.76 | CASP1 (0.56) | CASP1CASP7HSD17B10HSD17B1MAOA | |
| SCHEMBL31532073 | 0.76 | SRD5A1 (0.51) | CASP1CASP7HSD17B10HSD17B1BAZ2B | |
| SCHEMBL883773 | 0.76 | SRD5A1 (0.51) | CASP1CASP7HSD17B10HSD17B1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005070916-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |