Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.51 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10193085 | 0.89 | BAZ2B (0.65) | NPC1MAPTRAB9AHSD17B1BAZ2B | |
| SCHEMBL15106295 | 0.88 | RAB9A (0.77) | NPC1MAPTRAB9AHSD17B1S100A4 | |
| SCHEMBL17540279 | 0.86 | HSD17B1 (0.66) | NPC1MAPTRAB9AHSD17B1CASP1 | |
| SCHEMBL8283186 | 0.84 | CASP1 (0.50) | NPC1MAPTRAB9AHSD17B1CASP1 | |
| SCHEMBL29431442 | 0.83 | SRD5A2 (0.66) | MAPTRAB9AHSD17B1CASP1CASP7 | |
| SCHEMBL1275273 | 0.83 | SRD5A2 (0.66) | MAPTRAB9AHSD17B1CASP1CASP7 | |
| SCHEMBL4424596 | 0.82 | PARP10 (0.67) | NPC1MAPTRAB9AHSD17B1CASP1 | |
| SCHEMBL10518407 | 0.81 | CASP1 (0.52) | NPC1MAPTRAB9AHSD17B1CASP1 | |
| SCHEMBL9944563 | 0.81 | CASP1 (0.52) | NPC1MAPTRAB9AHSD17B1CASP1 | |
| SCHEMBL1091518 | 0.81 | CASP1 (0.56) | HSD17B1CASP1CASP7HSD17B10SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011018170-A2 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | WO | disclosed |
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |