Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944562 | 0.89 | MAOA (0.59) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL11806865 | 0.88 | SRD5A2 (0.59) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL1275273 | 0.83 | SRD5A2 (0.66) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL29431442 | 0.83 | SRD5A2 (0.66) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL1091518 | 0.81 | CASP1 (0.56) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL10518407 | 0.81 | CASP1 (0.52) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL8253223 | 0.81 | NPC1 (0.61) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL18724460 | 0.80 | SRD5A2 (0.47) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL8254416 | 0.79 | CASP1 (0.49) | CASP1CASP7HSD17B10HSD17B1SRD5A1 | |
| SCHEMBL10587731 | 0.78 | ALDH1A1 (0.55) | SRD5A1SRD5A2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| US-20120149910-A1 | Pesticidal Carboxamides | BAYER CROPSCIENCE AG (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20120149910-A1 | Pesticidal Carboxamides | BAYER CROPSCIENCE AG (DE) | 2012-06-14 | — | — | US | disclosed |
| WO-2011018170-A2 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149910-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | CASP1 640/4885CASP7 119/4885HSD17B10 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.