Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284460 | 0.92 | TRPC5 (0.47) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL8241916 | 0.89 | TRPC5 (0.49) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL8283652 | 0.87 | TRPC5 (0.42) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL8283653 | 0.86 | TRPC5 (0.50) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL8284462 | 0.85 | TRPC5 (0.56) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL14271799 | 0.84 | LMNA (0.41) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL8250145 | 0.83 | TRPC5 (0.54) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL4856873 | 0.82 | LMNA (0.40) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL8285134 | 0.81 | ALDH1A1 (0.38) | TRPC5LMNAMAPK1MAPTTSHR | |
| SCHEMBL14007607 | 0.81 | TRPC5 (0.56) | TRPC5LMNAMAPK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058871-A1 | MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |