Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 6/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284443 | 0.92 | BCHE (0.40) | HRH3BCHEACHEAPPTRPC5 | |
| SCHEMBL8284411 | 0.88 | NME2 (0.40) | HRH3BCHEACHEAPPALDH1A1 | |
| SCHEMBL8284441 | 0.86 | TRPC5 (0.42) | HRH3BCHEACHEAPPTRPC5 | |
| SCHEMBL4863925 | 0.84 | BCHE (0.37) | HRH3BCHEACHEAPPALDH1A1 | |
| SCHEMBL4866131 | 0.81 | EGFR (0.34) | HRH3BCHEACHEAPPALDH1A1 | |
| SCHEMBL8283653 | 0.76 | TRPC5 (0.50) | TRPC5ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14271721 | 0.74 | — | — | |
| SCHEMBL8241916 | 0.71 | TRPC5 (0.49) | TRPC5ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL8285136 | 0.70 | TRPC5 (0.47) | TRPC5ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8284458 | 0.69 | TRPC5 (0.48) | TRPC5ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058871-A1 | MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |