Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | TCF4 | P15884 | 2/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | FURIN | P09958 | 1/20 | 0.57 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543927 | 0.90 | KDM4E (0.59) | KDM4ETCF4CTNNB1ALDH1A1F2 | |
| SCHEMBL8369354 | 0.88 | TCF4 (0.80) | KDM4ETCF4CTNNB1KMT2ASMN1; SMN2 | |
| SCHEMBL25311928 | 0.88 | ALDH1A1 (0.61) | KDM4ETCF4CTNNB1ALDH1A1HTT | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL4057888 | 0.86 | IL1RN (0.65) | KDM4ETCF4CTNNB1ALDH1A1HTT | |
| SCHEMBL21761420 | 0.86 | ALDH1A1 (0.69) | KDM4EALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL936067 | 0.84 | AR (0.63) | KDM4ETCF4CTNNB1KMT2AMEN1 | |
| SCHEMBL10487708 | 0.83 | WDR5 (0.73) | ALDH1A1F2F10FURINCYTH2 | |
| SCHEMBL24312124 | 0.81 | FFAR4 (0.54) | KDM4ETCF4CTNNB1ALDH1A1CYTH2 | |
| SCHEMBL24102252 | 0.81 | TCF4 (0.73) | KDM4ETCF4CTNNB1ALDH1A1HTT | |
| SCHEMBL9818397 | 0.80 | WDR5 (0.69) | ALDH1A1F2F10FURINCYTH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113817150-B | Copolyester containing aromatic secondary amine structure and preparation method and application thereof | 四川大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-113817150-A | Copolyester containing aromatic secondary amine structure and preparation method and application thereof | 四川大学 | 2021-12-21 | — | — | CN | disclosed |
| US-20090042867-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | FUCHS KLAUS | 2009-02-12 | — | — | US | disclosed |
| US-20090042867-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | FUCHS KLAUS | 2009-02-12 | — | — | US | disclosed |
| WO-2007017509-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042867-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | PSEN1, PSEN2, MAOB | KDM4E 2630/4885TCF4 3592/4885CTNNB1 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.