Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992571 | 0.89 | REN (0.53) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL5710197 | 0.86 | REN (0.54) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL91287 | 0.84 | REN (0.55) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL1083640 | 0.83 | REN (0.54) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL8263807 | 0.83 | REN (0.60) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL27740106 | 0.81 | REN (0.43) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL78416 | 0.81 | REN (0.53) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL27740232 | 0.81 | REN (0.43) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL8282811 | 0.80 | HTR1A (0.60) | RENGRM5HTR1ASLC6A4TSHR | |
| SCHEMBL13139892 | 0.79 | REN (0.43) | RENGRM5HTR1ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987834-A2 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |