Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19752303 | 0.73 | GABRA1 (0.39) | ALDH1A1IDO1PKMPTAFRCHRM1 | |
| SCHEMBL11415417 | 0.71 | NISCH (0.38) | KDM4ELMNAPTAFRCHRM1 | |
| Hydrochloric Acid SCHEMBL10999066 | 0.69 | GABRA1 (0.37) | ALDH1A1HPGDPTAFRTP53HTR2A | |
| SCHEMBL1941287 | 0.68 | ALDH1A1 (0.40) | KDM4EMEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL27018073 | 0.67 | HDAC4 (0.47) | IDO1APAF1TDP2MAOAMAOB | |
| SCHEMBL29385734 | 0.64 | CES1 (0.45) | KDM4EMEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL249997 | 0.64 | CES1 (0.45) | KDM4EMEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL2797733 | 0.63 | LMNA (0.48) | KDM4EMEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL7214854 | 0.63 | ALDH1A1 (0.38) | KDM4EMEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL6487919 | 0.63 | CES1 (0.43) | KDM4EMEN1KMT2AALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051410-A9 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2005-07-28 | — | — | WO | disclosed |