Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82879 | 1.00 | CYP3A4 (1.00) | CYP3A4KCNH2KDM4EHPGDALDH1A1 | |
| SCHEMBL29478146 | 1.00 | CYP3A4 (1.00) | CYP3A4KCNH2KDM4EHPGDALDH1A1 | |
| SCHEMBL2083007 | 0.97 | CYP3A4 (0.94) | CYP3A4KCNH2KDM4EHPGDALDH1A1 | |
| SCHEMBL2083006 | 0.97 | CYP3A4 (0.94) | CYP3A4KCNH2KDM4EHPGDALDH1A1 | |
| SCHEMBL2083093 | 0.90 | CYP3A4 (0.82) | CYP3A4KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL2083095 | 0.90 | CYP3A4 (0.82) | CYP3A4KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL2081913 | 0.90 | CYP3A4 (0.81) | CYP3A4KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL2081915 | 0.90 | CYP3A4 (0.81) | CYP3A4KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL2082207 | 0.89 | CYP3A4 (0.79) | CYP3A4KCNH2KDM4EHPGDALDH1A1 | |
| SCHEMBL2082211 | 0.89 | CYP3A4 (0.79) | CYP3A4KCNH2KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129533-B2 | Method for production of quinolone-containing lyophilized preparation | DALICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | claimed |
| US-20080300403-A1 | Method for Production of Quinolone-Containing Lyophilized Preparation | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-12-04 | — | — | US | claimed |
| EP-1930006-A1 | METHOD FOR PRODUCTION OF QUINOLONE-CONTAINING LYOPHILIZED PREPARATION | Daiichi Sankyo Company, Limited (JP) | 2008-06-11 | — | — | EP | claimed |
| EP-1336611-B1 | DEHALOGENO COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2007-09-05 | — | — | EP | claimed |
| US-20070123560-A1 | Dehalogeno-compounds | DAIICHI PHARMACEUTICAL CO., LTD. | 2007-05-31 | — | — | US | claimed |
| US-20040063754-A1 | Dehalogeno compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | claimed |
| EP-1336611-A1 | DEHALOGENO COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-08-20 | — | — | EP | claimed |
| US-8129533-B2 | Method for production of quinolone-containing lyophilized preparation | DALICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-7902226-B2 | Dehalogeno-compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20090117205-A1 | Quinolone-containing medicinal composition | DAIICHI PHARMACEUTICAL CO., LTD (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20080300403-A1 | Method for Production of Quinolone-Containing Lyophilized Preparation | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-12-04 | — | — | US | disclosed |
| EP-1930006-A1 | METHOD FOR PRODUCTION OF QUINOLONE-CONTAINING LYOPHILIZED PREPARATION | Daiichi Sankyo Company, Limited (JP) | 2008-06-11 | — | — | EP | disclosed |
| EP-1336611-B1 | DEHALOGENO COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20070123560-A1 | Dehalogeno-compounds | DAIICHI PHARMACEUTICAL CO., LTD. | 2007-05-31 | — | — | US | disclosed |
| EP-1764102-A1 | QUINOLONE-CONTAINING MEDICINAL COMPOSITION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-20040063754-A1 | Dehalogeno compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1336611-A1 | DEHALOGENO COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300403-A1 | Method for Production of Quinolone-Containing Lyophilized Preparation | NQO2, TREH, CYP51A1 | CYP3A4 314/4885KCNH2 2623/4885KDM4E 2681/4885 |
| US-20040063754-A1 | Dehalogeno compounds | DEK, PGLS, RPS27L | CYP3A4 198/4885KCNH2 1597/4885KDM4E 2484/4885 |
| US-20090117205-A1 | Quinolone-containing medicinal composition | ABCB11, SLC47A1, AQP1 | CYP3A4 211/4885KCNH2 541/4885KDM4E 3440/4885 |
| US-20070123560-A1 | Dehalogeno-compounds | DEK, RPS27L, POLL | CYP3A4 277/4885KCNH2 1059/4885KDM4E 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.