Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289439 | 0.76 | GRIA4 (0.73) | GRIA2GRIA4 | |
| SCHEMBL4471245 | 0.74 | GRIA4 (0.50) | GRIA2GRIA4 | |
| Bicarbonate SCHEMBL9638235 | 0.71 | FFAR1 (0.71) | MAOBNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL9126144 | 0.71 | MAOB (0.90) | MAOBNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL21484965 | 0.70 | TSHR (0.55) | LMNA | |
| SCHEMBL4949143 | 0.70 | NR4A2 (0.90) | MAOBNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL22206786 | 0.70 | FFAR1 (0.61) | MAOBIKBKEGSTP1LMNAL3MBTL1 | |
| SCHEMBL16335060 | 0.70 | L3MBTL1 (0.46) | MAOBNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL22219371 | 0.70 | LMNA (0.59) | MAOBNR4A2NR4A1NR4A3MCL1 | |
| Hydrochloric Acid SCHEMBL8378883 | 0.69 | NR4A2 (0.87) | MAOBNR4A2NR4A1NR4A3SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040110-A1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |