Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289734 | 0.85 | ALDH1A1 (0.76) | ALDH1A1TSHRKDM4EALOX15HSD17B10 | |
| SCHEMBL8288576 | 0.77 | ALDH1A1 (0.71) | ALDH1A1TSHRKDM4EALOX15HSD17B10 | |
| SCHEMBL8289733 | 0.77 | ALDH1A1 (0.71) | ALDH1A1TSHRKDM4EALOX15HSD17B10 | |
| SCHEMBL5455543 | 0.74 | ALDH1A1 (0.78) | ALDH1A1TSHRKDM4EALOX15HSD17B10 | |
| SCHEMBL8290347 | 0.71 | ALDH1A1 (0.69) | ALDH1A1TSHRKDM4EALOX15HSD17B10 | |
| Oxalic Acid SCHEMBL34468543 | 0.68 | ALDH1A1 (0.70) | ALDH1A1TSHRKDM4EALOX15HSD17B10 | |
| SCHEMBL8288703 | 0.68 | LMNA (0.47) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL15369925 | 0.68 | POLB (1.00) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL34468524 | 0.68 | KMT2A (0.83) | ALDH1A1TSHRKDM4EALOX15HSD17B10 | |
| SCHEMBL8288718 | 0.67 | MEN1 (0.96) | ALDH1A1TSHRKDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |