Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288580 | 0.86 | FLT3 (0.45) | LMNAHPGDFLT3ALDH1A1MAPT | |
| SCHEMBL8288555 | 0.81 | ALDH1A1 (0.70) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8289733 | 0.74 | ALDH1A1 (0.71) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8288576 | 0.74 | ALDH1A1 (0.71) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13187811 | 0.73 | ALDH1A1 (0.47) | LMNAHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL8288594 | 0.70 | TP53 (0.59) | LMNAHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL8288598 | 0.68 | ALDH1A1 (0.54) | LMNAHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL8289585 | 0.68 | L3MBTL1 (0.61) | LMNAFLT3ALDH1A1MAPTMEN1 | |
| SCHEMBL8288708 | 0.68 | TP53 (0.67) | LMNAHPGDFLT3ALDH1A1MAPT | |
| SCHEMBL8288570 | 0.67 | MAPT (0.59) | LMNAHPGDALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |