Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289010 | 0.80 | HPGDS (0.38) | F10 | |
| SCHEMBL14085132 | 0.77 | TOP2A (0.44) | F10PDCD1LG2CD274 | |
| SCHEMBL7006039 | 0.75 | CHRNB2 (0.48) | F10PDCD1LG2CD274 | |
| SCHEMBL8286902 | 0.74 | PTAFR (0.46) | F10 | |
| SCHEMBL122260 | 0.72 | ADORA3 (0.46) | — | |
| SCHEMBL5502730 | 0.69 | TOP2A (0.36) | F10PDCD1LG2CD274 | |
| Water SCHEMBL9451273 | 0.68 | PTAFR (0.43) | F10 | |
| Water SCHEMBL9451270 | 0.68 | PTAFR (0.43) | F10 | |
| Hydrochloric Acid SCHEMBL6766285 | 0.68 | TOP2A (0.41) | — | |
| SCHEMBL8290031 | 0.67 | NISCH (0.49) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005032490-A2 | CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |