Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291498 | 1.00 | GAA (0.32) | GAABACE1F2F10PRSS1 | |
| SCHEMBL8050876 | 0.86 | BACE1 (0.31) | GAABACE1F2F10PRSS1 | |
| SCHEMBL8290280 | 0.86 | BACE1 (0.31) | GAABACE1F2F10PRSS1 | |
| SCHEMBL12606705 | 0.81 | PLG (0.32) | PLG | |
| SCHEMBL8289676 | 0.81 | — | — | |
| SCHEMBL8289679 | 0.81 | — | — | |
| SCHEMBL13685709 | 0.79 | CCR2 (0.33) | CCR2PLG | |
| SCHEMBL8289637 | 0.79 | CTSD (0.35) | GAA | |
| SCHEMBL13685625 | 0.79 | CTSD (0.35) | GAA | |
| SCHEMBL12607874 | 0.78 | ADAM17 (0.37) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030796-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |