Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292426 | 0.84 | HPGD (0.42) | USP2SLC6A2SLC6A4ALDH1A1KMT2A | |
| SCHEMBL8290869 | 0.83 | ACHE (0.46) | USP2SLC6A2SLC6A4ALDH1A1KMT2A | |
| SCHEMBL8300351 | 0.79 | SLC6A2 (0.59) | SLC6A2SLC6A4ALDH1A1KMT2AHPGD | |
| SCHEMBL8300989 | 0.75 | QDPR (0.45) | SLC6A2SLC6A4ACHEBCHEASAH1 | |
| SCHEMBL8695469 | 0.73 | SLC6A2 (0.42) | USP2SLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL8290868 | 0.73 | CHRM3 (0.41) | ALDH1A1KMT2AHPGDHSD17B10KDM4E | |
| SCHEMBL8292427 | 0.72 | KDM4E (0.39) | USP2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL8300836 | 0.72 | ASAH1 (0.45) | ACHEBCHEASAH1 | |
| SCHEMBL8300839 | 0.71 | ASAH1 (0.37) | SLC6A2SLC6A4KDM4EACHEBCHE | |
| SCHEMBL8297441 | 0.70 | ASAH1 (0.37) | HPGDHSD17B10ACHEBCHEASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637586-B1 | 2-(Piperidin-4-yl, pyridin-4-yl and tetrahydropyridin-4-yl)-benzofuran-7-carbamate derivatives, their preparation and their use as acetylcholinesterase inhibitors | HOECHST MARION ROUSSEL INC (US) | 1999-06-02 | — | — | EP | claimed |
| EP-0637586-B1 | 2-(Piperidin-4-yl, pyridin-4-yl and tetrahydropyridin-4-yl)-benzofuran-7-carbamate derivatives, their preparation and their use as acetylcholinesterase inhibitors | HOECHST MARION ROUSSEL INC (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0637586-A1 | 2-(Piperidin-4-yl, pyridin-4-yl and tetrahydropyridin-4-yl)benzofuran-7-ol and carbamate derivatives, their preparation and their use as acetylcholinesterase inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-02-08 | — | — | EP | disclosed |