Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11324175 | 0.98 | CYP2D6 (0.42) | CYP2D6MAPTHCAR2LDHALDHB | |
| SCHEMBL11633136 | 0.82 | ALDH1A1 (0.50) | MAPTHCAR2LDHALDHBGAA | |
| SCHEMBL11324161 | 0.79 | GAA (0.36) | CYP2D6MAPTHCAR2GAAKMT2A | |
| SCHEMBL11324784 | 0.79 | GAA (0.36) | CYP2D6MAPTGAAKMT2ATSHR | |
| SCHEMBL11633637 | 0.70 | POLB (0.56) | MAPTKMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL3114000 | 0.70 | — | — | |
| Water SCHEMBL15331255 | 0.68 | LMNA (0.58) | HCAR2GAAKMT2AJAK2THRB | |
| SCHEMBL15859525 | 0.68 | HCAR2 (0.55) | HCAR2LDHALDHBKMT2ATSHR | |
| SCHEMBL17222521 | 0.68 | ALDH1A1 (0.33) | CYP2D6MAPTGAAKMT2ALMNA | |
| SCHEMBL15564067 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485082-A1 | METHODS FOR SYNTHESIS OF PRODRUGS FROM 1-ACYL-ALKYL DERIVATIVES AND COMPOSITIONS THEREOF | Xenoport, Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003077902-A1 | METHODS FOR SYNTHESIS OF PRODRUGS FROM 1-ACYL-ALKYL DERIVATIVES AND COMPOSITIONS THEREOF | XENOPORT, INC. (US) | 2003-09-25 | — | — | WO | claimed |
| US-20030171303-A1 | Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof | ARBOR PHARMACEUTICALS, LLC | 2003-09-11 | — | — | US | claimed |
| US-5530129-A | Process for the preparation of 1,2,4-triazine-3,5-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | claimed |
| EP-0695743-A1 | Process for the preparation of 1,2,4-triazine-3,5-diones | BAYER AG (DE) | 1996-02-07 | — | — | EP | claimed |
| JP-8059634-A | — | — | None | — | — | JP | disclosed |
| US-12533354-B2 | Triaryl compounds for treatment of PD-L1 diseases | CHEMOCENTRYX, INC. (US) | 2026-01-27 | — | — | US | disclosed |
| WO-2025137568-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-115583919-B | Preparation method of 6-oxyalkyl 1,2, 4-triazine-3, 5 (2H, 4H) -diketone derivative | 河北工业大学 | 2024-04-19 | — | — | CN | disclosed |
| US-20240109863-A1 | 2-PYRIDONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | KPC PHARMACEUTICALS, INC (CN) | 2024-04-04 | — | — | US | disclosed |
| EP-4273139-A1 | 2-PYRIDONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | KPC Pharmaceuticals, Inc. (CN) | 2023-11-08 | — | — | EP | disclosed |
| CN-116802176-A | Oxindoles and methods of use thereof | 阿利戈斯治疗公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2003077902-A1 | METHODS FOR SYNTHESIS OF PRODRUGS FROM 1-ACYL-ALKYL DERIVATIVES AND COMPOSITIONS THEREOF | XENOPORT, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| US-20030171303-A1 | Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof | ARBOR PHARMACEUTICALS, LLC | 2003-09-11 | — | — | US | disclosed |
| US-5530129-A | Process for the preparation of 1,2,4-triazine-3,5-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| US-5530129-A | Process for the preparation of 1,2,4-triazine-3,5-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| JP-H0859634-A | PREPARATION OF 1,2,4-TRIAZINE-3,5-DIONES | BAYER AG | 1996-03-05 | — | — | JP | disclosed |
| EP-0695743-A1 | Process for the preparation of 1,2,4-triazine-3,5-diones | BAYER AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-4198407-A | Substituted 2-phenyl-1,2,4-triazine-3,5(2H,4H)-diones, and coccidiostatic agents containing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4081441-A | PENICILLANIC ACIDS | BRISTOL-MYERS COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109863-A1 | 2-PYRIDONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | PTH1R, MC2R, TSHR | CYP2D6 335/4885MAPT 4410/4885HCAR2 383/4885 |
| US-12533354-B2 | Triaryl compounds for treatment of PD-L1 diseases | CD274, PDCD1LG2, PDCD1 | CYP2D6 151/4885MAPT 4110/4885HCAR2 132/4885 |
| US-20030171303-A1 | Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof | AADAC, UGT1A1, AGPAT5 | CYP2D6 25/4885MAPT 4481/4885HCAR2 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.