Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829306 | 0.82 | CYP2D6 (0.43) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL6046336 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL17281433 | 0.81 | MAPT (0.46) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11324175 | 0.80 | CYP2D6 (0.42) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL5269625 | 0.72 | POLB (0.54) | ALDH1A1GAAKMT2AMAPTRXFP1 | |
| SCHEMBL1196085 | 0.70 | — | — | |
| SCHEMBL5791378 | 0.67 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL17272789 | 0.65 | MAPT (0.61) | ALDH1A1GAAKMT2AMAPTMEN1 | |
| SCHEMBL15859525 | 0.65 | HCAR2 (0.55) | ALDH1A1KMT2AHCAR2LDHALDHB | |
| SCHEMBL28136550 | 0.64 | NSD2 (0.47) | ALDH1A1GAAKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119220636-A | Biological activity detection kit based on luciferase reporter gene | 大连博格林生物科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-119220636-A | Biological activity detection kit based on luciferase reporter gene | 大连博格林生物科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| US-20230293524-A1 | OTIC FORMULATIONS FOR DRUG-INDUCED OTOTOXICITY | SPIRAL THERAPEUTICS INC. | 2023-09-21 | — | — | US | disclosed |
| EP-3661932-B1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | PROMEGA CORP (US) | 2021-10-06 | — | — | EP | disclosed |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | PROMEGA CORPORATION (US) | 2021-10-05 | — | — | US | disclosed |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | PROMEGA CORPORATION (US) | 2021-10-05 | — | — | US | disclosed |
| WO-2021087408-A1 | OTIC FORMULATIONS FOR DRUG-INDUCED OTOTOXICITY | OTONOMY, INC. (US) | 2021-05-06 | — | — | WO | disclosed |
| EP-3661932-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | Promega Corporation (US) | 2020-06-10 | — | — | EP | disclosed |
| US-20190040449-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2019-02-07 | — | — | US | disclosed |
| WO-2019028272-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | PROMEGA CORPORATION (US) | 2019-02-07 | — | — | WO | disclosed |
| US-20190040449-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2019-02-07 | — | — | US | disclosed |
| EP-3146066-B1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | PROMEGA CORP (US) | 2018-03-14 | — | — | EP | disclosed |
| US-9676997-B2 | Compositions and methods for stabilizing luminogenic substrates | PROMEGA CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676997-B2 | Compositions and methods for stabilizing luminogenic substrates | PROMEGA CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| EP-3146066-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | Promega Corporation (US) | 2017-03-29 | — | — | EP | disclosed |
| US-20150337198-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2015-11-26 | — | — | US | disclosed |
| WO-2015179864-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | PROMEGA CORPORATION (US) | 2015-11-26 | — | — | WO | disclosed |
| US-20150337198-A1 | COMPOSITIONS AND METHODS FOR STABILIZING LUMINOGENIC SUBSTRATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2015-11-26 | — | — | US | disclosed |
| US-4081441-A | PENICILLANIC ACIDS | BRISTOL-MYERS COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040449-A1 | COMPOSITIONS AND METHODS FOR STABILIZING BENZOTHIAZOLE LUCIFERIN ANALOGS | TK1, TYMP, NUDT1 | ALDH1A1 2006/4885GAA 1393/4885KMT2A 1287/4885 |
| US-11136615-B2 | Compositions and methods for stabilizing benzothiazole luciferin analogs | TK1, TYMP, NUDT1 | ALDH1A1 2006/4885GAA 1393/4885KMT2A 1287/4885 |
| US-20230293524-A1 | OTIC FORMULATIONS FOR DRUG-INDUCED OTOTOXICITY | OTC, SLC26A4, OAT | ALDH1A1 121/4885GAA 2616/4885KMT2A 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.