Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363623 | 0.88 | L3MBTL1 (0.50) | L3MBTL1MAPTALDH1A1LMNAADORA3 | |
| SCHEMBL14363610 | 0.84 | L3MBTL1 (0.46) | L3MBTL1MAPTALDH1A1LMNAGAA | |
| SCHEMBL16067418 | 0.82 | L3MBTL1 (0.51) | L3MBTL1MAPTGAAPDK2KDM4E | |
| SCHEMBL14363630 | 0.82 | L3MBTL1 (0.51) | L3MBTL1MAPTGAAPDK2KDM4E | |
| SCHEMBL9987876 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MAPTALDH1A1GAATSHR | |
| SCHEMBL9782317 | 0.76 | L3MBTL1 (0.38) | L3MBTL1MAPTALDH1A1LMNAGAA | |
| SCHEMBL25426498 | 0.76 | L3MBTL1 (0.53) | L3MBTL1MAPTGAATSHRCA12 | |
| SCHEMBL15677598 | 0.76 | ACACB (0.44) | MAPTTSHRNPSR1DGAT1NPC1 | |
| SCHEMBL9782308 | 0.74 | STAT3 (0.40) | L3MBTL1MAPTALDH1A1LMNAGAA | |
| SCHEMBL14363634 | 0.74 | L3MBTL1 (0.77) | L3MBTL1MAPTLMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947834-B2 | Substituted quinoxalines, their preparation and their therapeutical use as 11βHSD1 modulators | SANOFI-AVENTIS (FR) | 2011-05-24 | — | — | US | disclosed |
| US-7947834-B2 | Substituted quinoxalines, their preparation and their therapeutical use as 11βHSD1 modulators | SANOFI-AVENTIS (FR) | 2011-05-24 | — | — | US | disclosed |
| US-20090176775-A1 | DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SANOFI-AVENTIS (FR) | 2009-07-09 | — | — | US | disclosed |
| US-20090176775-A1 | DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SANOFI-AVENTIS (FR) | 2009-07-09 | — | — | US | disclosed |
| US-20070259874-A1 | Phosphodiesterase Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2007-11-08 | — | — | US | disclosed |
| US-20070259874-A1 | Phosphodiesterase Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2007-11-08 | — | — | US | disclosed |
| WO-2005051931-A2 | PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-09 | — | — | WO | disclosed |
| US-4160829-A | ANTIBIOTICS | GIST-BROCADES N.V. (NL) | 1979-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176775-A1 | DERIVATIVES OF UREAS OF PIPERIDINE OR PYRROLIDINE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | HSD11B1, HSD3B1, ADH1C | L3MBTL1 4567/4885MAPT 1529/4885ALDH1A1 46/4885 |
| US-20070259874-A1 | Phosphodiesterase Inhibitors | PDE4A, PDE3B, PDE7A | L3MBTL1 4801/4885MAPT 2797/4885ALDH1A1 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.