Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 4/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296560 | 0.88 | HSD17B1 (0.37) | FASNCCR5CHRM2CHRM3HTT | |
| SCHEMBL8296765 | 0.85 | HTT (0.47) | CCR5CHRM2CHRM3HTTATM | |
| SCHEMBL8296818 | 0.82 | SYK (0.38) | FASNF2DPP4 | |
| SCHEMBL8296574 | 0.82 | PKM (0.60) | FASNCCR5ATMPKMDPP4 | |
| SCHEMBL8295064 | 0.82 | KMT2A (0.38) | CCR5ATMPKML3MBTL1F2 | |
| SCHEMBL8294266 | 0.82 | F2 (0.41) | CCR5CHRM2CHRM3ATMHPGD | |
| SCHEMBL8296819 | 0.81 | NR3C1 (0.36) | ATMF2OPRD1 | |
| SCHEMBL8295897 | 0.80 | ATM (0.52) | LMNAHTTATMHPGDTSHR | |
| SCHEMBL8296568 | 0.79 | F2 (0.36) | CCR5ATMF2 | |
| SCHEMBL6246057 | 0.79 | ANPEP (0.35) | CCR5LMNAATMHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |