Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296765 | 0.92 | HTT (0.47) | HTTGPR88CCR5DPP4DPP9 | |
| SCHEMBL8295051 | 0.89 | MLYCD (0.40) | HTTPOLBGPR88CCR5DPP4 | |
| SCHEMBL8295053 | 0.88 | HTT (0.37) | HTTPOLBCCR5DPP4DPP9 | |
| SCHEMBL8296775 | 0.82 | POLB (0.40) | HTTPOLBRAB9A | |
| SCHEMBL8295492 | 0.77 | FASN (0.41) | HTTCCR5DPP4DPP9F2 | |
| SCHEMBL8294266 | 0.73 | F2 (0.41) | CCR5DPP4DPP9F2 | |
| SCHEMBL6246057 | 0.73 | ANPEP (0.35) | CCR5DPP4DPP9F2 | |
| SCHEMBL6246060 | 0.73 | ANPEP (0.35) | CCR5DPP4DPP9F2 | |
| SCHEMBL2773909 | 0.71 | CNR2 (0.45) | CNR1CNR2HTTPOLBNR1H4 | |
| SCHEMBL8294261 | 0.71 | ACHE (0.37) | HTTCCR5DPP4DPP9F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |