Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8295051 | 0.89 | MLYCD (0.40) | POLBRAB9AHTT | |
| SCHEMBL8295053 | 0.88 | HTT (0.37) | POLBRAB9AKMT2AGAAHTT | |
| SCHEMBL8296765 | 0.88 | HTT (0.47) | KMT2AHTT | |
| SCHEMBL8296567 | 0.82 | CNR1 (0.40) | POLBRAB9AHTT | |
| SCHEMBL8295492 | 0.76 | FASN (0.41) | HTT | |
| SCHEMBL8296560 | 0.74 | HSD17B1 (0.37) | POLBRAB9AEPHX1KMT2AHTT | |
| SCHEMBL2473498 | 0.72 | MLYCD (0.45) | HDAC1HDAC8HDAC6EPHX1MEN1 | |
| SCHEMBL2050355 | 0.72 | MLYCD (0.45) | HDAC1HDAC8HDAC6EPHX1MEN1 | |
| SCHEMBL8295896 | 0.71 | EPHX2 (0.62) | POLBRAB9AMEN1KMT2AMAPT | |
| SCHEMBL8294266 | 0.71 | F2 (0.41) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |