Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23117963 | 0.83 | ALOX5 (0.59) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL70688 | 0.81 | KDM4E (0.71) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL77381 | 0.81 | CA1 (0.77) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| Salicylhydroxamic Acid SCHEMBL21530845 | 0.79 | KDM4E (1.00) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| Salicylhydroxamic Acid SCHEMBL144849 | 0.79 | KDM4E (1.00) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL1783556 | 0.77 | ALDH1A1 (0.64) | KDM4ESMN1; SMN2GAAHPGDHTT | |
| SCHEMBL27583795 | 0.77 | MEN1 (0.62) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL161525 | 0.77 | KDM4E (0.65) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL1799299 | 0.77 | KDM4E (0.65) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL3225038 | 0.77 | KDM4E (0.65) | KDM4ESMN1; SMN2GAAMPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063505-B | Anti-GAL 3 antibodies and uses thereof | 真和制药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117916269-A | Method for preventing aggregation of proteins | 真和制药有限公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2005007124-A2 | SUBSTITUTED DIHYDROPYRIMIDINE INHIBITORS OF CALCIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-01-27 | — | — | WO | disclosed |