Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.62 |
| ▸ | HTR7 | P34969 | 7/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.58 |
| ▸ | DRD2 | P14416 | 5/20 | 0.58 |
| ▸ | HTR6 | P50406 | 4/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443108 | 0.93 | HTR1A (0.60) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| SCHEMBL8302931 | 0.87 | OPRM1 (0.56) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| SCHEMBL8299871 | 0.86 | HTR1A (0.57) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| SCHEMBL8303317 | 0.85 | SLC6A4 (0.54) | OPRM1OPRK1OPRL1SLC6A4HTR6 | |
| SCHEMBL29534522 | 0.85 | HTR1A (0.56) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| SCHEMBL7529023 | 0.84 | HTR1A (0.64) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| SCHEMBL8303049 | 0.84 | DRD2 (0.67) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL9030489 | 0.83 | HTR1A (0.63) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| SCHEMBL8298953 | 0.82 | HTR1A (0.50) | HTR1AHTR7OPRM1OPRK1OPRL1 | |
| SCHEMBL8877428 | 0.82 | OPRM1 (0.67) | HTR1AHTR7OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |